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Drug-DNA Interaction Protocols von Keith R. Fox (2009, Gebundene Ausgabe)

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DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. even clinical investigators such as oncologists may find this book quite useful. Dies gilt insbesondere wenn eine ISBN durch den Verlag doppelt vergeben wurde.

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Produktinformation

DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases. Each of these advances has required the availability and development of an arsenal of techniques for probing the interactions in both qualitative and quantitative terms. This v- ume of Methods in Molecular Biology brings together several techniques that are currently useful for examining these interactions. Some of these are updates on ones that were included in the earlier volume (Methods in Molecular Biology 90), published 12 years ago, while others are new.

Produktkennzeichnungen

Herausgeber
Keith R. Fox
ISBN-10
1603274170
ISBN-13
9781603274173
eBay Product ID (ePID)
81991137

Produkt Hauptmerkmale

Produktart
Lehrbuch
Sprache
Englisch
Anzahl der Seiten
332 Seiten
Verlag
Humana Press
Publikationsname
Drug-Dna Interaction Protocols
Autor
Keith R. Fox
Format
Gebundene Ausgabe
Erscheinungsjahr
2009

Zusätzliche Produkteigenschaften

Hörbuch
No
Inhaltsbeschreibung
Hc Runder Rücken Kaschiert
Item Length
26cm
Item Height
2cm
Item Width
18cm
Nummer Innerhalb der Serie
613
Item Weight
899g
Buchreihe
Methods in Molecular Biology

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Drug-DNA Interaction Protocols von Keith R. Fox (2009, Gebundene Ausgabe)

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Produktinformation

Produktkennzeichnungen

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Zusätzliche Produkteigenschaften

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