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Tumors of the Central Nervous System, Volume 4: Brain Tumors (Part 2) by M.A. Hayat (Hardcover, 2011)

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ISBN-13: 9789400717053, 978-9400717053. Information on pathways ([url] hedgehog) facilitates targeted therapies in cancer. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized.

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This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized. The need for supportive measures for survivors of brain cancer is pointed out, so is the quality of life monitoring. The need of rehabilitation therapy for patients with primary and metastatic brain tumors is also emphasized. Role of MicroRNA in distinguishing primary tumors from metastatic primary tumors is discussed. Advantages and limitations of chemotherapy (e.g., temozolomide and doxorubicin) are discussed. The complexity of tumor to tumor transfer is explained; examples discussed are: brain metastases from breast cancer and brain metastases fro non-small cell lung carcinoma. Identification and characterization of biomarkers, including those for metastatic brain tumors, are presented. Genomic analysis for identifying clinically relevant subtypes of glioblastoma is included. A large number of imaging modalities are detailed to study progression and invasion of gliomas

Product Identifiers

PublisherSpringer

ISBN-139789400717053

eBay Product ID (ePID)176514563

Product Key Features

Number of Pages386 Pages

Publication NameTumors of the Central Nervous System, Volume 4: Brain Tumors (Part 2)

LanguageEnglish

SubjectMedicine, Surgery, Radiology

Publication Year2011

TypeTextbook

AuthorM.A. Hayat

SeriesTumors of the Central Nervous System

FormatHardcover

Dimensions

Item Height260 mm

Item Weight1074 g

Item Width193 mm

Volume4

Additional Product Features

EditorM.A. Hayat

Country/Region of ManufactureNetherlands