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Insulin - The Crooked Timber: A History from Thick Brown Muck to Wall Street

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Características del artículo

Estado
Nuevo: Libro nuevo, sin usar y sin leer, que está en perfecto estado; incluye todas las páginas sin ...
Book Title
Insulin - The Crooked Timber: A History from Thick Brown Muck to
Publication Date
2022-01-20
ISBN
9780192855381

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Product Identifiers

Publisher
Oxford University Press, Incorporated
ISBN-10
0192855387
ISBN-13
9780192855381
eBay Product ID (ePID)
5050433333

Product Key Features

Number of Pages
480 Pages
Language
English
Publication Name
Insulin-The Crooked Timber : a History from Thick Brown Muck to Wall Street Gold
Publication Year
2022
Subject
Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), History
Type
Textbook
Author
Kersten T. Hall
Subject Area
Science, Medical
Format
Hardcover

Dimensions

Item Height
1.1 in
Item Weight
33.4 Oz
Item Length
9.4 in
Item Width
6.4 in

Additional Product Features

Intended Audience
Trade
LCCN
2021-943457
Reviews
"[uses] a blend of profound research, lively writing and personal knowledge of diabetes" -- Andrew Robinson, Nature "The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International "The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph, A fascinating book by an author with excellent credentials, well written and meticulously researched., "... comprehensive account of the modern medical history of the hormone..." -- Jerome Groopman, New York Review of Books "[uses] a blend of profound research, lively writing and personal knowledge of diabetes" -- Andrew Robinson, Nature "The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International "The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph "It is a good read and scholarly account." -- Arpan Banerjee , Hektoen International Journal, "The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International "The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph, "... comprehensive account of the modern medical history of the hormone..." -- Jerome Groopman, New York Review of Books"The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International"The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph"It is a good read and scholarly account." -- Arpan Banerjee , Hektoen International Journal"Insulin-the Crooked Timber is essential reading for anyone concerned with the history of insulin." -- Social History of Alcohol and Drugs."Hall's The Crooked Timber expertly combines careful attention to the science with thoughtful consideration of its historical and philosophical dimensions." -- Neelanjana Ray, History and Philosophy of the Life Sciences"I expected it to be interesting - or at least the part dealing with Dick [my father] and Archer's work. What I didn't expect was that it would be a 'page turner' from start to finish!" -- Mr Patrick Synge, Son of Nobel laureate Richard Synge (Chemistry 1952), "[uses] a blend of profound research, lively writing and personal knowledge of diabetes" -- Andrew Robinson "The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International "The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph, "... comprehensive account of the modern medical history of the hormone..." -- Jerome Groopman, New York Review of Books "[uses] a blend of profound research, lively writing and personal knowledge of diabetes" -- Andrew Robinson, Nature "The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International "The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph, "... comprehensive account of the modern medical history of the hormone..." -- Jerome Groopman, New York Review of Books"The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International"The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph"It is a good read and scholarly account." -- Arpan Banerjee , Hektoen International Journal"Insulin-the Crooked Timber is essential reading for anyone concerned with the history of insulin." -- Social History of Alcohol and Drugs."Hall's The Crooked Timber expertly combines careful attention to the science with thoughtful consideration of its historical and philosophical dimensions." -- Neelanjana Ray, History and Philosophy of the Life Sciences, "The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph, "... comprehensive account of the modern medical history of the hormone..." -- Jerome Groopman, New York Review of Books"The lengthy bibliography and endnotes are a testament to the extensive research that has been carried out to produce this fascinating account." -- Arpan K. Banerjee, Hektoen International"The story of insulin over the past 100 years, as the historian of science (and former molecular biologist) Kersten Hall shows in this dense and fascinating book, is also a microcosm of developments in science more widely, and of changes in the politics and economics of healthcare. [...] The pleasures of this book lie mainly in the storytelling detail and the gossipy richness of the lives, friendships and feuds glimpsed in the hubbub of decades pursuing the improvement of human health." -- Steven Poole, Daily Telegraph"It is a good read and scholarly account." -- Arpan Banerjee , Hektoen International Journal"Insulin-the Crooked Timber is essential reading for anyone concerned with the history of insulin." -- Social History of Alcohol and Drugs.
Dewey Edition
23
Illustrated
Yes
Dewey Decimal
615.365
Table Of Content
PrefaceLooking a Gift Horse in the Mouth?IntroductionTaming the Tiger1. The Pissing Evil - a colourful description of diabetes by 17th century English physician Thomas Willis2. Thick Brown Muck - Canadian scientist Fred Banting wins the Nobel Prize for the discovery of insulin... and is furious3. The Vision of Ezekiel - clinicians are stunned at the power of insulin to save lives, but it proves to be a double-edged sword4. A Greek Tragedy - German clinician Georg Zuelzer snatches defeat from the jaws of victory5. The Wasp's Nest - insulin proves to be a poisoned chalice for its discoverers6. Be Careful What You Wish For - the case of Romanian scientist Nicolai Paulesco underlines the truth of an old proverb7. 'In Praise of Wool' - the humble wool fibre sets in motion a revolution in biochemistry8. A Boastful Undertaking - a discovery made in a fume-filled stable offers the key to unlocking insulin9. The Blobs That Won a Nobel Prize - or two, all thanks to some coloured spots on a piece of filter paper10. The Prophet in the Labyrinth - biochemist Erwin Chargaff helps unlock the secrets of DNA, but fears where this may lead11. The Clone Wars - a conflict in which insulin proves to be a decisive weapon12. Wall Street Gold - in an act of modern day alchemy, insulin makes stock market history13. 'Don't You Want Cheap Insulin?' - What is it exactly that we want from science? And does the story of insulin have any lessons for us today?BibliographyFigures List and Acknowledgements for ImagesAcknowledgementsEnd notes
Synopsis
One hundred years after a milestone medical discovery, 'Insulin - The Crooked Timber' tells the story of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune., Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. One hundred years after a milestone medical discovery, 'Insulin - The Crooked Timber' tells the story of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Yet when Canadian doctor Frederick Banting was told in 1923 that he had won the Nobel Prize for this life-saving discovery, he was furious. For the prize had not been awarded to him alone - but jointly with a man whom he felt had no right to this honour. The human story behind this discovery is one of ongoing political and scientific controversy. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, 'Insulin - The Crooked Timber' reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes such as two little known scientists whose work on wool fibres, carried out in a fume-filled former stable, not only proved to be crucial in unravelling the puzzle of insulin but ushered in a revolution in biology. It was the author's own shocking diagnosis with Type 1 diabetes that prompted him to sit down and write this book, but this story has lessons for us all about what technology can - and more importantly cannot - do for us. As the world pins its hopes on effective and lasting vaccines against Covid-19, these lessons from the story of insulin have never been more relevant., Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. One hundred years after a milestone medical discovery, 'Insulin - The Crooked Timber' tells the story of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune.Yet when Canadian doctor Frederick Banting was told in 1923 that he had won the Nobel Prize for this life-saving discovery, he was furious. For the prize had not been awarded to him alone - but jointly with a man whom he felt had no right to this honour. The human story behind this discovery is one of ongoing political and scientific controversy.Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, 'Insulin - The Crooked Timber' reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes such as two little known scientists whose work on wool fibres, carried out in a fume-filled former stable, not only proved to be crucial in unravelling the puzzle of insulin but ushered in a revolution in biology.It was the author's own shocking diagnosis with Type 1 diabetes that prompted him to sit down and write this book, but this story has lessons for us all about what technology can - and more importantly cannot - do for us. As the world pins its hopes on effective and lasting vaccines against Covid-19, these lessons from the story of insulin have never been more relevant., Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. One hundred years after a milestone medical discovery, 'Insulin - The Crooked Timber' tells the story of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune.Yet when Canadian doctor Frederick Banting was told in 1923 that he had won the Nobel Prize for this life-saving discovery, he was furious. For the prize had not been awarded to him alone - but jointly with a man whom he felt had no right to this honour. The human story behind this discovery is one of ongoing political and scientific controversy.Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s though to the present day, 'Insulin - The Crooked Timber' reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes such as two little known scientists whose work on wool fibres, carried out in a fume-filled former stable, not only proved to be crucial in unravelling the puzzle of insulin but ushered in a revolution in biology.It was the author's own shocking diagnosis with Type 1 diabetes that prompted him to sit down and write this book, but this story has lessons for us all about what technology can - and more importantly cannot - do for us. As the world pins its hopes on effective and lasting vaccines against Covid-19, these lessons from the story of insulin have never been more relevant.
LC Classification Number
QP572.I5

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