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Introduction to Statistical Methods for Clinical Trials 1st Edition by Thomas D.
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Características del artículo
- Estado
- ISBN-13
- 9781584880271
- Book Title
- Introduction to Statistical Methods for Clinical Trials
- ISBN
- 9781584880271
Acerca de este producto
Product Identifiers
Publisher
CRC Press LLC
ISBN-10
1584880279
ISBN-13
9781584880271
eBay Product ID (ePID)
2667239
Product Key Features
Number of Pages
464 Pages
Language
English
Publication Name
Introduction to Statistical Methods for Clinical Trials
Subject
Clinical Medicine, Biostatistics, Probability & Statistics / General, Pharmacology
Publication Year
2007
Type
Textbook
Subject Area
Mathematics, Medical
Series
Chapman and Hall/Crc Texts in Statistical Science Ser.
Format
Hardcover
Dimensions
Item Height
1.2 in
Item Weight
36.1 Oz
Item Length
9.5 in
Item Width
6.4 in
Additional Product Features
Intended Audience
College Audience
LCCN
2007-036202
Reviews
e There is much good material in this book. The individual chapters are well written and cover the technical aspects as well. A major strength is the ordering of topics to follow the thought process used in the development and implementation of a protocol from defining the question to reporting results. There are careful discussions on fundamental principles and the pivotal role played by statistics is well brought out. e there is much that practicing pharmaceutical statisticians will find useful in this book. They will find the coverage of fundamental principles useful and the technical content of the book a good reference source. e e"Pharmaceutical Statistics, 2010 efits the need for a contemporary text and handbook that is oriented toward the clinical trial statistician. I highly recommend it and look forward to using it as both a primary and supplemental text in our curriculum, as well as a research resource. e"James J. Dignam, University of Chicago, JASA, March 2009 The (technical) statistical content is the main focus of the book and this is what helps it to stand apart from most others on clinical trials (even the more obviously statistically orientated ones). It takes the reader to quite a technical background that would serve him or her well if moving on to research problems in the various areas covered, yet does not lose sight of practical issues. e For those of us with the interest (and need) to grapple with these more statistical issues, I wholeheartedly recommend it. e"Biometrics, December 2008 eThe book is very well written and clear. e the authors generally strike the right balance for the intended audience. The inclusion of many historically important as well as contemporary examples to illustrate various points throughout the text is a major strength, as is the inclusion of several modern topics not seen in other texts. As a basis for a course in clinical trials for graduate students in biostatistics, this book is outstanding. In addition, statisticians in the pharmaceutical industry, government, or academia e will find this text extremely informative and useful.e e"Michael P. McDermott, University of Rochester Medical Center, Journal of Biopharmaceutical Statistics, 2008, ... There is much good material in this book. The individual chapters are well written and cover the technical aspects as well. A major strength is the ordering of topics to follow the thought process used in the development and implementation of a protocol from defining the question to reporting results. There are careful discussions on fundamental principles and the pivotal role played by statistics is well brought out. ... there is much that practicing pharmaceutical statisticians will find useful in this book. They will find the coverage of fundamental principles useful and the technical content of the book a good reference source. ... --Pharmaceutical Statistics, 2010 ... fits the need for a contemporary text and handbook that is oriented toward the clinical trial statistician. I highly recommend it and look forward to using it as both a primary and supplemental text in our curriculum, as well as a research resource. --James J. Dignam, University of Chicago, JASA, March 2009 The (technical) statistical content is the main focus of the book and this is what helps it to stand apart from most others on clinical trials (even the more obviously statistically orientated ones). It takes the reader to quite a technical background that would serve him or her well if moving on to research problems in the various areas covered, yet does not lose sight of practical issues. ... For those of us with the interest (and need) to grapple with these more statistical issues, I wholeheartedly recommend it. --Biometrics, December 2008 ...The book is very well written and clear. ... the authors generally strike the right balance for the intended audience. The inclusion of many historically important as well as contemporary examples to illustrate various points throughout the text is a major strength, as is the inclusion of several modern topics not seen in other texts. As a basis for a course in clinical trials for graduate students in biostatistics, this book is outstanding. In addition, statisticians in the pharmaceutical industry, government, or academia ... will find this text extremely informative and useful." --Michael P. McDermott, University of Rochester Medical Center, Journal of Biopharmaceutical Statistics, 2008, There is much good material in this book. The individual chapters are well written and cover the technical aspects as well. A major strength is the ordering of topics to follow the thought process used in the development and implementation of a protocol from defining the question to reporting results. There are careful discussions on fundamental principles and the pivotal role played by statistics is well brought out. there is much that practicing pharmaceutical statisticians will find useful in this book. They will find the coverage of fundamental principles useful and the technical content of the book a good reference source. �Pharmaceutical Statistics, 2010 fits the need for a contemporary text and handbook that is oriented toward the clinical trial statistician. I highly recommend it and look forward to using it as both a primary and supplemental text in our curriculum, as well as a research resource. �James J. Dignam, University of Chicago, JASA, March 2009 The (technical) statistical content is the main focus of the book and this is what helps it to stand apart from most others on clinical trials (even the more obviously statistically orientated ones). It takes the reader to quite a technical background that would serve him or her well if moving on to research problems in the various areas covered, yet does not lose sight of practical issues. For those of us with the interest (and need) to grapple with these more statistical issues, I wholeheartedly recommend it. �Biometrics, December 2008 The book is very well written and clear. the authors generally strike the right balance for the intended audience. The inclusion of many historically important as well as contemporary examples to illustrate various points throughout the text is a major strength, as is the inclusion of several modern topics not seen in other texts. As a basis for a course in clinical trials for graduate students in biostatistics, this book is outstanding. In addition, statisticians in the pharmaceutical industry, government, or academia will find this text extremely informative and useful. �Michael P. McDermott, University of Rochester Medical Center, Journal of Biopharmaceutical Statistics, 2008, … There is much good material in this book. The individual chapters are well written and cover the technical aspects as well. A major strength is the ordering of topics to follow the thought process used in the development and implementation of a protocol from defining the question to reporting results. There are careful discussions on fundamental principles and the pivotal role played by statistics is well brought out. … there is much that practicing pharmaceutical statisticians will find useful in this book. They will find the coverage of fundamental principles useful and the technical content of the book a good reference source. … -Pharmaceutical Statistics, 2010 … fits the need for a contemporary text and handbook that is oriented toward the clinical trial statistician. I highly recommend it and look forward to using it as both a primary and supplemental text in our curriculum, as well as a research resource. -James J. Dignam, University of Chicago, JASA, March 2009 The (technical) statistical content is the main focus of the book and this is what helps it to stand apart from most others on clinical trials (even the more obviously statistically orientated ones). It takes the reader to quite a technical background that would serve him or her well if moving on to research problems in the various areas covered, yet does not lose sight of practical issues. … For those of us with the interest (and need) to grapple with these more statistical issues, I wholeheartedly recommend it. -Biometrics, December 2008 …The book is very well written and clear. … the authors generally strike the right balance for the intended audience. The inclusion of many historically important as well as contemporary examples to illustrate various points throughout the text is a major strength, as is the inclusion of several modern topics not seen in other texts. As a basis for a course in clinical trials for graduate students in biostatistics, this book is outstanding. In addition, statisticians in the pharmaceutical industry, government, or academia … will find this text extremely informative and useful. -Michael P. McDermott, University of Rochester Medical Center, Journal of Biopharmaceutical Statistics, 2008, ... There is much good material in this book. The individual chapters are well written and cover the technical aspects as well. A major strength is the ordering of topics to follow the thought process used in the development and implementation of a protocol from defining the question to reporting results. There are careful discussions on fundamental principles and the pivotal role played by statistics is well brought out. ... there is much that practicing pharmaceutical statisticians will find useful in this book. They will find the coverage of fundamental principles useful and the technical content of the book a good reference source. ... --Pharmaceutical Statistics, 2010 ... fits the need for a contemporary text and handbook that is oriented toward the clinical trial statistician. I highly recommend it and look forward to using it as both a primary and supplemental text in our curriculum, as well as a research resource. --James J. Dignam, University of Chicago, JASA, March 2009 The (technical) statistical content is the main focus of the book and this is what helps it to stand apart from most others on clinical trials (even the more obviously statistically orientated ones). It takes the reader to quite a technical background that would serve him or her well if moving on to research problems in the various areas covered, yet does not lose sight of practical issues. ... For those of us with the interest (and need) to grapple with these more statistical issues, I wholeheartedly recommend it. --Biometrics, December 2008 ...The book is very well written and clear. ... the authors generally strike the right balance for the intended audience. The inclusion of many historically important as well as contemporary examples to illustrate various points throughout the text is a major strength, as is the inclusion of several modern topics not seen in other texts. As a basis for a course in clinical trials for graduate students in biostatistics, this book is outstanding. In addition, statisticians in the pharmaceutical industry, government, or academia ... will find this text extremely informative and useful." --Michael P. McDermott, University of Rochester Medical Center, Journal of Biopharmaceutical Statistics, 2008
Dewey Edition
22
Illustrated
Yes
Dewey Decimal
615.50724
Table Of Content
Preface. Introduction to Clinical Trials. Defining the Question. Study Design. Sample Size. Randomization. Data Collection and Quality Control. Survival Analysis. Longitudinal Data. Quality of Life. Data Monitoring and Interim Analysis. Selected Issues in the Analysis. Closeout and Reporting. Special Topics. Appendix. References. Index.
Synopsis
This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. It covers basic experimental design, sample size, randomization procedures, interim and survival analyses, quality of life assessment, and longitudinal methods. The book describes all phases of a clinical trial and explores the advantages of and objections to the intent-to-treat principle as well as its implementation. With exercises at the end of most chapters, it also illustrates methods using examples with real data from a variety of disease areas, including heart and lung diseases, cancer, and AIDS., Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, from cardiovascular disease to cancer to AIDS. Based on the authors' collective experiences in this field, Introduction to Statistical Methods for Clinical Trials presents various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. After reviewing the history, ethics, protocol, and regulatory issues of clinical trials, the book provides guidelines for formulating primary and secondary questions and translating clinical questions into statistical ones. It examines designs used in clinical trials, presents methods for determining sample size, and introduces constrained randomization procedures. The authors also discuss how various types of data must be collected to answer key questions in a trial. In addition, they explore common analysis methods, describe statistical methods that determine what an emerging trend represents, and present issues that arise in the analysis of data. The book concludes with suggestions for reporting trial results that are consistent with universal guidelines recommended by medical journals. Developed from a course taught at the University of Wisconsin for the past 25 years, this textbook provides a solid understanding of the statistical approaches used in the design, conduct, and analysis of clinical trials.
LC Classification Number
R853
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- c***a (121)- Votos emitidos por el comprador.Últimos 6 mesesCompra verificadaThe seller was very responsive and answered me on a timely matter. The product itself came in its packaging and was new, not used at all. The packaging was not beat up or anything, safely delivered to my mailbox. No mix ups and zero stress with delivery. The price for the product is completely understandable for the product. I really appreciate the seller and I am very happy to have purchased through this seller. Completely trustable!
- m***4 (1614)- Votos emitidos por el comprador.Últimos 6 mesesCompra verificadaLeaving positive feedback because 1) item was packed well & arrived as described 2) seller did give partial refund when subsequent price dropped below org purchase price. 3) communication was quick However, there was a downside to this transaction -item listed as in-stock but ended up waiting nearly a month for them to get it from their distributer then ship it to me (bought June 29th, arrived around July 21). Auction said 12-15 days. Better clarity would have prevented lot of frustrationStreet Fighter II - Guile (Player 2) Figure - 6 Inch (#365698737394)
- n***i (4)- Votos emitidos por el comprador.Mes pasadoCompra verificadaMy statue was exactly as described, it was un-opened and in perfect condition! Totally wirth the price. Getting it shipped took a little long but the seller was very responsive when I messaged and sent me the tracking as soon as it was available. Plus they did a good job packaging it well enough that despite being banged up on the outside my item was completely undamaged.