Signal Transduction: Principles, Pathways, and Processes by Lewis Cantley (Engli

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Características del artículo

Estado
Nuevo: Libro nuevo, sin usar y sin leer, que está en perfecto estado; incluye todas las páginas sin ...
ISBN-13
9781621821816
Book Title
Signal Transduction: Principles, Pathways, and Processes
ISBN
9781621821816
Categoría

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Product Identifiers

Publisher
Cold Spring Harbor Laboratory Press
ISBN-10
1621821811
ISBN-13
9781621821816
eBay Product ID (ePID)
246501975

Product Key Features

Number of Pages
452 Pages
Publication Name
Signal Transduction: Principles, Pathways, and Processes
Language
English
Publication Year
2013
Subject
Life Sciences / Molecular Biology, Life Sciences / Cell Biology, Life Sciences / Developmental Biology
Type
Textbook
Subject Area
Science
Author
Tony Hunter
Format
Trade Paperback

Dimensions

Item Height
1 in
Item Weight
44.8 Oz
Item Length
10.9 in
Item Width
8.5 in

Additional Product Features

Intended Audience
Scholarly & Professional
Reviews
"...the editors recruited the most distinguished scientists in special areas as coauthors. Through the contributions of about 60 individual authors, a book developed, which covers not only the state of the art of signal transduction, but a volume that can serve as a source of knowledge and stimulating inspiration for interested students and investigators." - The Quarterly Review of Biology "...a one-stop shop for signaling information....it excels in providing information on just about any aspect of signal transduction imaginable...written by a veritable who's who of the signaling field...it is a magnum opus and should be a reference source..." - Science Signaling "The comprehensive nature of this superb textbook, as well as its careful and lucid writing, clear illustrations, and extensive references, makes it a must read for graduate students and research personnel." - Choice "I give this book an excellent review, with regard to its clear explanations and use of diagramming to illustrate cell communication." - Olive Branch United Blog, "...the editors recruited the most distinguished scientists in special areas as coauthors. Through the contributions of about 60 individual authors, a book developed, which covers not only the state of the art of signal transduction, but a volume that can serve as a source of knowledge and stimulating inspiration for interested students and investigators." - The Quarterly Review of Biology"...a one-stop shop for signaling information....it excels in providing information on just about any aspect of signal transduction imaginable...written by a veritable who's who of the signaling field...it is a magnum opus and should be a reference source..." - Science Signaling"The comprehensive nature of this superb textbook, as well as its careful and lucid writing, clear illustrations, and extensive references, makes it a must read for graduate students and research personnel." - Choice"I give this book an excellent review, with regard to its clear explanations and use of diagramming to illustrate cell communication." - Olive Branch United Blog
Table Of Content
Preface Foreword Edmond Fischer SECTION I. GENERAL PRINCIPLES AND MECHANISMS 1 Signals and Receptors Carl-Henrik Heldin, Benson Lu, Ron Evans, and J. Silvio Gutkind 2 Protein Regulation in Signal Transduction Michael J. Lee and Michael B. Yaffe 3 Second Messengers Alexandra C. Newton, Martin D. Bootman, and John D. Scott 4 Signaling Networks: Information Flow, Computation, and Decision Making Evren U. Azeloglu and Ravi Iyengar SECTION II. SIGNALING PATHWAYS MAP Kinase Pathways Deborah K. Morrison The PI3K-PKB/Akt Pathway Brian A. Hemmings and David F. Restuccia mTOR Signaling Mathieu Laplante and David M. Sabatini Calcium Signaling Martin D. Bootman The Cyclic AMP Pathway Paolo Sassone-Corsi Wnt Signaling Roel Nusse Hedgehog Signaling Philip W. Ingham Notch Signaling Raphael Kopan Signaling by the TGFb Superfamily Jeffrey L. Wrana The JAK/STAT Pathway Douglas A. Harrison Toll-Like Receptor Signaling Kian-Huat Lim and Louis M. Staudt Immunoreceptor Signaling Lawrence E. Samelson Signaling by Nuclear Receptors Richard Sever and Christopher K. Glass The Hippo Pathway Kieran F. Harvey and Iswar K. Hariharan SECTION III. SIGNALING PROCESSES 5 Signaling Pathways that Control Cell Proliferation Robert J. Duronio and Yue Xiong 6 Signaling Pathways that Regulate Cell Division Nicholas Rhind and Paul Russell 7 Signaling in Control of Cell Growth and Metabolism Patrick S. Ward and Craig B. Thompson 8 Signaling Networks that Regulate Cell Migration Peter Devreotes and Alan Rick Horwitz 9 Signaling Pathways in Cell Polarity Luke Martin McCaffrey and Ian G. Macara 10 Signaling Mechanisms Controlling Cell Fate and Embryonic Patterning Norbert Perrimon, Chrysoula Pitsouli, and Ben-Zion Shilo 11 Signaling by Sensory Receptors David Julius and Jeremy Nathans 12 Synaptic Signaling in Learning and Memory Mary B. Kennedy 13 Signaling in Muscle Contraction Ivana Y. Kuo and Barbara E. Ehrlich 14 Organismal Carbohydrate and Lipid Homeostasis D. Grahame Hardie 15 Signaling in Innate Immunity and Inflammation Kim Newton and Vishva M. Dixit 16 Signaling in Lymphocyte Activation Doreen Cantrell 17 Vertebrate Reproduction Sally Kornbluth and Rafael Fissore 18 Cell Signaling and Stress Responses Gökhan S. Hotamisligil and Roger J. Davis 19 Cell Death Signaling Douglas R. Green and Fabien Llambi 20 Subversion of Cell Signaling by Pathogens Neal M. Alto and Kim Orth 21 Signal Transduction in Cancer Richard Sever and Joan S. Brugge 22 Outlook Jeremy Thorner, Tony Hunter, Lewis C. Cantley, and Richard Sever Index
Synopsis
Cells must respond to a wide variety of signals. These include hormones, growth factors, morphogens, and environmental stress, as well as signals from internal regulators and checkpoints. A complex network of signal transduction pathways within the cell ensures that these signals are relayed to the correct molecular targets and that the cell responds appropriately. This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. Taking a novel approach, it first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function. The book is essential reading for students learning about signal transduction for the first time. It will also be a vital reference for all cell, molecular, and developmental biologists and pharmacologists, neurobiologists, and immunologists studying processes regulated by cell signaling., Signal transduction pathways are molecular circuits that define how cells communicate with each other and respond to their environment. This new textbook for the first time provides a comprehensive view of the subject by covering both the basic mechanisms involved and the roles of signal transduction in fundamental biological processes. · Introduces the fundamental principles of signal transduction · Provides 'route maps' for all the major signaling pathways · Explains in detail how signaling pathways are integrated to control key cellular process

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