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Product Identifiers
PublisherCRC Press LLC
ISBN-100367399857
ISBN-139780367399856
eBay Product ID (ePID)25038416049
Product Key Features
Number of Pages612 Pages
Publication NameHandbook of Drug Metabolism
LanguageEnglish
Publication Year2019
SubjectPharmacy, Biochemistry, Chemistry / General
TypeTextbook
Subject AreaScience, Medical
AuthorThomas Woolf
FormatTrade Paperback
Dimensions
Item Weight39.9 Oz
Item Length10 in
Item Width7 in
Additional Product Features
Intended AudienceCollege Audience
Table Of ContentFundamental Aspects of Drug Metabolism. Factors Affecting Drug Metabolism. Technologies. Metabolism in Drug Discovery and Development.
SynopsisBringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.