Imagen 1 de 1
Galería
Imagen 1 de 1
¿Quieres vender uno?
Suicide Gene Therapy: Methods and Reviews by Caroline J. Springer (English) Pape
USD136,48
Aproximadamente117,50 EUR
Estado:
Nuevo
Libro nuevo, sin usar y sin leer, que está en perfecto estado; incluye todas las páginas sin defectos. Consulta el anuncio del vendedor para obtener más información.
Oops! Looks like we're having trouble connecting to our server.
Refresh your browser window to try again.
Envío:
Gratis Economy Shipping.
Ubicado en: Fairfield, Ohio, Estados Unidos
Entrega:
Entrega prevista entre el mié. 27 ago. y el lun. 8 sep. a 94104
Devoluciones:
30 días para devoluciones. El comprador paga el envío de la devolución..
Pagos:
Compra con confianza
El vendedor asume toda la responsabilidad de este anuncio.
N.º de artículo de eBay:395142213260
Última actualización el 29 ene 2025 02:24:29 H.EspVer todas las actualizacionesVer todas las actualizaciones
Características del artículo
- Estado
- ISBN-13
- 9781617372834
- Book Title
- Suicide Gene Therapy
- ISBN
- 9781617372834
Acerca de este producto
Product Identifiers
Publisher
Humana Press
ISBN-10
1617372838
ISBN-13
9781617372834
eBay Product ID (ePID)
109165469
Product Key Features
Number of Pages
Xiv, 555 Pages
Language
English
Publication Name
Suicide Gene Therapy : Methods and Reviews
Subject
Oncology
Publication Year
2010
Type
Textbook
Subject Area
Medical
Series
Methods in Molecular Medicine Ser.
Format
Trade Paperback
Dimensions
Item Weight
29.3 Oz
Item Length
9 in
Item Width
6 in
Additional Product Features
Intended Audience
Scholarly & Professional
Dewey Edition
21
Reviews
"This is a good book for those working in the area of suicide gene therapy that can serve both as a reference to senior investigators as well as a primer to new lab members and researchers outside the field who are trying to get a flavor of the state of the field."-Doody's Health Sciences Book Review Journal "...an extensive review of the theoretical background of suicide gene therapy that covers all major aspects..." - ChemBioChem "Authoritative and up-to-date...provides the experimental means to advance its future development and therapeutic applications." - Anticancer Research
Series Volume Number
90
Number of Volumes
1 vol.
Illustrated
Yes
Dewey Decimal
616.99/4042
Table Of Content
to the Background, Principles, and State of the Art in Suicide Gene Therapy.- to Vectors for Suicide Gene Therapy.- Construction of VNP20009.- Nonreplicating DNA Viral Vectors for Suicide Gene Therapy.- Replication-Selective Oncolytic Adenoviruses.- Retroviral Vectors for Suicide Gene Therapy.- Nonviral Liposomes.- Peptide- and Polymer-Based Gene Delivery Vehicles.- Design of Prodrugs for Suicide Gene Therapy.- Cytochrome P450-Based Gene Therapies for Cancer.- Tumor Sensitization to Purine Analogs by E. coli PNP.- Enzyme-Prodrug Systems.- Enzyme-Prodrug Systems.- Methods to Improve Efficacy in Suicide Gene Therapy Approaches.- Extracellular ?-Glucuronidase for Gene-Directed Enzyme-Prodrug Therapy.- Enhancement of Suicide Gene Prodrug Activation by Random Mutagenesis.- Combination Suicide Gene Therapy.- Immune Response to Suicide Gene Therapy.- Targeting Cancer With Gene Therapy Using Hypoxia as a Stimulus.- Radiation-Activated Antitumor Vectors.- In Vitro and In Vivo Models for Evaluation of GDEPT.- Suicide Gene Therapy in Liver Tumors.- Clinical Trials With GDEPT.- The Nitroreductase/CB1954 Enzyme-Prodrug System.- Side Effects of Suicide Gene Therapy.- Antibody-Directed Enzyme-Prodrug Therapy.- Bioreductive Prodrugs for Cancer Therapy.
Synopsis
Gene therapy has expanded rapidly over the last decade. The number of clinical trials reported by 2001 included 532 protocols and 3436 patients. Phase I trials predominate with 359 trials of 1774 patients versus Phase II (57 trials with 507 patients) and Phase III (3 trials of 251 patients). The disease overwhelmingly targeted by gene therapy is cancer: involving 331 trials with 2361 patients. Despite the somewhat disappointing results of clinical trials to date, gene therapy offers tremendous promise for the future of cancer therapy. The area of gene therapy is vast, and both malignant and nonmalignant cells can be targeted. Suicide Gene Therapy: Methods and Reviews covers gene therapy that targets malignant cells in a treatment that has become known as "suicide gene therapy. " Basically, this approach uses the transduction of cancer cells with a gene for a foreign enzyme that, when expressed, is able to activate a nontoxic prodrug into a highly cytotoxic drug able to kill the cancer cell population. This is a major area in cancer gene therapy--in 2001 this technique was represented by 52 clinical protocols with a total of 567 patients. Additional trials used multiple gene therapy protocols that also involved suicide gene therapy (83 with 497 patients), indicating that the interest in this area is considerable. Suicide Gene Therapy: Methods and Reviews aims to cover comprehensively, both in theoretical and practical terms, the rapidly evolving area of suicide gene therapy for cancer.
LC Classification Number
RC254-282
Descripción del artículo del vendedor
Información de vendedor profesional
Acerca de este vendedor
grandeagleretail
98,2% de votos positivos•2,8 millones artículos vendidos
Registrado como vendedor profesional
Votos de vendedor (1.055.248)
- w***i (875)- Votos emitidos por el comprador.Mes pasadoCompra verificadaAbsolutely Wonderful Seller!! Terrific Item As Described!!! Great Service and Communication!! Shipped In Waterproof Packaging!! I Received Item In About One Week!! Very Pleased With Seller! I Will Buy From This Seller Again!!
- e***_ (17)- Votos emitidos por el comprador.Últimos 6 mesesCompra verificadaSeller handles a massive inventory so I give them grace on the slow processing and shipping. They were very communicative and prompt with their response when I messaged in asking about it. Book was in good condition as described. Small ding on the page edges which wasn't mentioned, but that's fairly common even at your typical book store. Still a good value and I'd buy from them again.
- 0***i (5)- Votos emitidos por el comprador.Últimos 6 mesesCompra verificadaThe first item arrived with some damage to the inside back cover, but the seller responded immediately, assuring me they’d provide a replacement, and even told me I could keep the original. They were upfront about a short delay, and gave a clear estimated ship date, and followed up right on time once it shipped. The replacement arrived in perfect condition and exactly as described. I really appreciated their transparency and professionalism. Would definitely buy from them again!
grandeagleretail
98,2% de votos positivos•2,8 millones artículos vendidos
Registrado como vendedor profesional
Votos de vendedor (1.055.248)
- w***i (875)- Votos emitidos por el comprador.Mes pasadoCompra verificadaAbsolutely Wonderful Seller!! Terrific Item As Described!!! Great Service and Communication!! Shipped In Waterproof Packaging!! I Received Item In About One Week!! Very Pleased With Seller! I Will Buy From This Seller Again!!
- e***_ (17)- Votos emitidos por el comprador.Últimos 6 mesesCompra verificadaSeller handles a massive inventory so I give them grace on the slow processing and shipping. They were very communicative and prompt with their response when I messaged in asking about it. Book was in good condition as described. Small ding on the page edges which wasn't mentioned, but that's fairly common even at your typical book store. Still a good value and I'd buy from them again.
- 0***i (5)- Votos emitidos por el comprador.Últimos 6 mesesCompra verificadaThe first item arrived with some damage to the inside back cover, but the seller responded immediately, assuring me they’d provide a replacement, and even told me I could keep the original. They were upfront about a short delay, and gave a clear estimated ship date, and followed up right on time once it shipped. The replacement arrived in perfect condition and exactly as described. I really appreciated their transparency and professionalism. Would definitely buy from them again!