Classics in Total Synthesis IV

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Características del artículo

Estado
Nuevo: Libro nuevo, sin usar y sin leer, que está en perfecto estado; incluye todas las páginas sin ...
Country of Origin
Germany
Educational Level
Adult & Further Education
Personalized
No
Level
Advanced
ISBN
9783527348770
Categoría

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Product Identifiers

Publisher
Wiley & Sons, Incorporated, John
ISBN-10
3527348778
ISBN-13
9783527348770
eBay Product ID (ePID)
15070486160

Product Key Features

Number of Pages
688 Pages
Language
English
Publication Name
Classics in Total Synthesis IV : New Targets, Strategies, Methods
Publication Year
2025
Subject
Life Sciences / Biochemistry, Chemistry / Physical & Theoretical, Chemistry / Industrial & Technical
Type
Textbook
Author
Stephan Rigol, K. C. Nicolaou, Ruocheng Yu
Subject Area
Science
Format
Trade Paperback

Dimensions

Item Height
0.6 in
Item Weight
24.1 Oz
Item Length
9.6 in
Item Width
6.7 in

Additional Product Features

Intended Audience
College Audience
Table Of Content
1. Introduction: Total Synthesis Marching on with New Methods and Strategies and with Molecules for Biology and Medicine 2. Halichondrin B and Norhalichondrin B 3. Daphmanidin E 4. Epicoccin G and (-)-Acetylaranotin 5. Taiwaniadducts B, C, and D 6. Schindilactone A 7. Welwitindolinones 8. Ryanodine and Ryanodol 9. Gedunin, Mitrephorone A, and Antiretroviral Agent Islatravir 10. Trioxacarcins 11. Aplyviolene 12. Dixiamycin B 13. Ingenol 14. Cardamom Peroxide, Nodulisporic Acid C, and Bilobalide 15. Batrachotoxin and Conidiogenones 16. Gukulenin B and C-H Functionalization
Synopsis
Fourth volume of a classic in the field of organic synthesis, describing retrosynthetic analysis and total synthesis of important molecules Classics in Total Synthesis IV is a compilation of highly important synthetic methods which lead to complex molecules with valuable properties. From the complex architectures of natural products to the streamlined synthesis of functional molecules, each chapter in Classics in Total Synthesis IV unfolds a unique story. The interplay of mechanisms, reactivity, selectivity, and stereochemical aspects is thoroughly examined, echoing the pedagogical format that has become synonymous with this series. Well-designed graphics are included throughout, and all important parts of the reaction sequences are highlighted. This volume encapsulates the culmination of new methodologies, emerging trends, and a selection of significant total syntheses undertaken from 2009 to 2022 while additionally including two earlier syntheses from 1979 and 1992 for comparison and to highlight the development of organic synthesis over the past decades. The careful balance between historical context, comments on the molecules' impact to humankind, and the design and execution aspects of each synthesis creates a narrative that is not only clear but also intellectually stimulating. Written by K. C. Nicolaou, Ruocheng Yu and Stephan Rigol, Classics in Total Synthesis IV includes 16 chapters covering: Coupling and rearrangement reactions Recent advances in nonenzymatic enantioselective cyclization Cycloaddition and annulation reactions C−H functionalization and transition metal-mediated C−H activation Electroorganic chemistry and visible-light photoredox catalysis HAT-initiated olefin hydrogenation, isomerization, and hydrofunctionalization Joining its predecessors in weaving together the threads of scientific discovery, challenge, and intellectual pursuit and establishing strong connections with biology and medicine, Classics in Total Synthesis IV is an essential reference for all future and present synthetic organic chemists.

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