Systems Biology: Properties of Reconstructed Networks

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Características del artículo

Estado
En buen estado: Libro que se ha leído pero que está en buen estado. Daños mínimos en la tapa, ...
Release Year
2006
Book Title
Systems Biology: Properties of Reconstructed Networks
ISBN
9780521859035
Categoría

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Product Identifiers

Publisher
Cambridge University Press
ISBN-10
0521859034
ISBN-13
9780521859035
eBay Product ID (ePID)
49213787

Product Key Features

Number of Pages
336 Pages
Language
English
Publication Name
Systems Biology : Properties of Reconstructed Networks
Subject
Life Sciences / Cell Biology, Life Sciences / Genetics & Genomics
Publication Year
2006
Type
Textbook
Author
Bernhard Palsson
Subject Area
Science
Format
Hardcover

Dimensions

Item Height
7.1 in
Item Weight
28.2 Oz
Item Length
10.3 in
Item Width
0.8 in

Additional Product Features

Intended Audience
College Audience
LCCN
2005-035008
Dewey Edition
22
Reviews
'... [deserves] serious attention from any quantitative scientist or physicist who hopes to learn about modern biology. ... a welcome departure from the typical biology textbook. ... a very readable introduction to the subject ... this is an exciting time for biology. The author exposes readers to enough material that the research literature in quantitative systems biology should become accessible.' Physics Today, "Systems Biology is a very readable introduction to the subject... make[s] it clear that this is an exciting time for biology." Nigel Goldenfeld, Physics Today, '… [deserves] serious attention from any quantitative scientist or physicist who hopes to learn about modern biology … a welcome departure from the typical biology textbook … a very readable introduction to the subject … this is an exciting time for biology. The author exposes readers to enough material that the research literature in quantitative systems biology should become accessible.' Physics Today
Illustrated
Yes
Dewey Decimal
572.80285
Table Of Content
Preface; 1. Introduction; 2. Basic concepts in systems biology; Part I. Reconstruction of Biochemical Networks: 3. Metabolic networks; 4. Regulatory networks; 5. Signalling networks; Part II. Mathematical Representation of Reconstructed Networks: 6. Basic features of S; 7. Topological properties; 8. Fundamental subspaces; 9. Null space of S; 10. The left null space of S; 11. The row and column spaces of S; Part III. Capabilities of Reconstructed Networks: 12. Dual causality; 13. Properties of solution spaces; 14. Sampling properties of solution spaces; 15. Finding functional states; 16. Parametric sensitivity; 17. Epilogue; Appendix A: nomenclature and abbreviations; Appendix B: E. coli core metabolic network; Bibliography; Index.
Synopsis
This textbook devoted to systems biology describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The links between the mathematical ideas and biological processes are made clear, and the book reflects the irreversible trend of increasing mathematical content in biology education. Therefore to assist both teacher and student, Palsson provides problem sets on an associated website., Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The new discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This textbook describes how to model networks, determine their properties, and relate these to phenotypic functions. Some knowledge of linear algebra and biochemistry is required, since the book reflects the irreversible trend of increasing mathematical content in biology education., Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This textbook, devoted to systems biology, describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites are some knowledge of linear algebra and biochemistry. Though the links between the mathematical ideas and biological processes are made clear, the book reflects the irreversible trend of increasing mathematical content in biology education. Therefore to assist both teacher and student, in an associated website Palsson provides problem sets, projects and Powerpoint slides, and keeps the presentation in the book concrete with illustrative material and experimental results., This textbook in systems biology describes how to model networks, how to determine their properties and how to relate these to phenotypic functions.
LC Classification Number
QH324.2 .P35 2006

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