G-PROTEIN-COUPLED RECEPTOR DIMERS (THE RECEPTORS) By Katharine Herrick-davis

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ISBN-10
3319601725
Publication Name
Humana Press
Type
Hardcover
Item Height
9.21 inches
ISBN
9783319601724

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Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-10
3319601725
ISBN-13
9783319601724
eBay Product ID (ePID)
237523596

Product Key Features

Book Title
G-Protein-Coupled Receptor Dimers
Number of Pages
Xvii, 501 Pages
Language
English
Topic
Life Sciences / Neuroscience, Chemistry / Organic
Publication Year
2017
Illustrator
Yes
Genre
Science
Author
Giuseppe Di Giovanni
Book Series
The Receptors Ser.
Format
Hardcover

Dimensions

Item Weight
316.9 Oz
Item Length
9.3 in
Item Width
6.1 in

Additional Product Features

Series Volume Number
33
Number of Volumes
1 vol.
Table Of Content
Part I. Introduction.- 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family.- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization.- 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors.- Part II. Receptors.- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer.- 5. Extreme Vetting of Dopamine Receptor Oligomerization.- 6. Serotonin receptors.- 7. Cannabinoid and Opioid Receptor Heteromers.- 8. Di/oligomerization of Glycoprotein Hormone Receptors.- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses.- 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior.- 11. Receptors and RAMPs.- 12. Obligatory Heterodimerization of GABAB Receptor.- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking.- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance.- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches.- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization.- Part IV. Physiology and Therapeutic Potential.- 17. Allosterism within GPCR Oligomers: Back to Symmetry.- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers.- 19. Heteromers form Novel Signaling Complexes.- 20. Heteroreceptor Complexes Implicated in Parkinson's Disease.
Synopsis
Comprehensive overview of the major GCPR dimers Contributors are some of the leading experts in this field Addresses both typical and pathological aspects and explores therapeutic potential, G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved. In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.
LC Classification Number
RC321-580

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