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Product Identifiers

PublisherOxford University Press, Incorporated

ISBN-100195084772

ISBN-139780195084771

eBay Product ID (ePID)880144

Product Key Features

Number of Pages1352 Pages

Publication NameExperimental and Clinical Neurotoxicology

LanguageEnglish

SubjectNeurology, Toxicology

Publication Year2000

FeaturesRevised

TypeTextbook

AuthorHerbert H. Schaumburg

Subject AreaMedical

FormatHardcover

Dimensions

Item Height2.6 in

Item Weight117.5 Oz

Item Length8.7 in

Item Width11.2 in

Additional Product Features

Edition Number2

Intended AudienceScholarly & Professional

LCCN98-018540

Dewey Edition21

Reviews"If you want to have and encyclopedia of how, why, and what is involved with neurotoxic effects, here's the volume to pursue!... This is a well-organized and carefully prepared edited reference book.... It will serve as the premier source for neurotoxic information for years to come.Clinicians, researchers, and particularly toxicologists should be greatly indebted to the editors and publisher for compiling and making available this excellent authoritative text." --Veterinary and Human Toxicology, From reviews of the first edition: "... impact of synthesizing and consolidating a whole body of knowledge so as to literally create and legitimize a new field in clinical neurology ... a brilliant new beacon on the horizon ... a comprehensive and scholarly statement of current knowledge ... an indispensable map for anyone planning in these charted or unchartered waters ... this book will soon join the esteemed rank of now classic books ... by such persons as H. Houston Merritt, Goodman and Cecil and Loeb, Lehninger and even Rachel Carson - Neurology, "The new edition of this book is long overdue and will be warmly welcomed. The book has been expanded and reorganized, and now covers an enormous spectrum of neurotoxic disorders. It is clear that this book will rapidly become the standard reference in the field, and deservedly so. It willfill an important role for many years to come. Its encyclopedic nature, will make it an important addition to all institutional libraries, as well as an invaluable resource to those with a special interest in neurotoxicology." -- Michael Aminoff MD, Muscle and Nerve, Dec 2000, "Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, pithy reference work for specialists in public health and the legal profession." Oxford University Press, "If you want to have and encyclopedia of how, why, and what is involved with neurotoxic effects, here's the volume to pursue!... This is a well-organized and carefully prepared edited reference book.... It will serve as the premier source for neurotoxic information for years to come. Clinicians, researchers, and particularly toxicologists should be greatly indebted to the editors and publisher for compiling and making available this excellent authoritativetext." --Veterinary and Human Toxicology"Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, pithy reference work for specialists in public health and the legal profession." Oxford University Press"It is almost 20 years since the appearance of Spencer and Schaumburg's ground-breaking volume on experimental and clinical neurotoxicology, which gave us a comprehensive survey of the subject as understood at the time. This new edition is greatly welcomed, since the original edition is now long out of date. Browsing through the catalogue is a journey through the realms of biology and pharmacology where untold dangers await. This book will be a sound source ofinformation for a wide circle of practitioners in the wards and scientists in the laboratory for a long time to come." --J.B. Cavanagh, Brain, Vol. 123, Part 12, Dec 2000"The new edition of this book is long overdue and will be warmly welcomed. The book has been expanded and reorganized, and now covers an enormous spectrum of neurotoxic disorders. It is clear that this book will rapidly become the standard reference in the field, and deservedly so. It will fill an important role for many years to come. Its encyclopedic nature, will make it an important addition to all institutional libraries, as well as an invaluable resourceto those with a special interest in neurotoxicology." -- Michael Aminoff MD, Muscle & Nerve, Dec 2000, "It is almost 20 years since the appearance of Spencer and Schaumburg's ground-breaking volume on experimental and clinical neurotoxicology, which gave us a comprehensive survey of the subject as understood at the time. This new edition is greatly welcomed, since the original edition is nowlong out of date. Browsing through the catalogue is a journey through the realms of biology and pharmacology where untold dangers await. This book will be a sound source of information for a wide circle of practitioners in the wards and scientists in the laboratory for a long time to come." --J.B.Cavanagh, Brain, Vol. 123, Part 12, Dec 2000, "The new edition of this book is long overdue and will be warmly welcomed.The book has been expanded and reorganized, and now covers an enormous spectrumof neurotoxic disorders. It is clear that this book will rapidly become thestandard reference in the field, and deservedly so. It will fill an importantrole for many years to come. Its encyclopedic nature, will make it an importantaddition to all institutional libraries, as well as an invaluable resource tothose with a special interest in neurotoxicology." -- Michael Aminoff MD, Muscleand Nerve, Dec 2000, "It is almost 20 years since the appearance of Spencer and Schaumburg'sground-breaking volume on experimental and clinical neurotoxicology, which gaveus a comprehensive survey of the subject as understood at thetime."--Brain, "If you want to have and encyclopedia of how, why, and what is involvedwith neurotoxic effects, here's the volume to pursue!... This is awell-organized and carefully prepared edited reference book.... It will serve asthe premier source for neurotoxic information for years to come. Clinicians,researchers, and particularly toxicologists should be greatly indebted to theeditors and publisher for compiling and making available this excellentauthoritative text." --Vet Human Toxicol, "Indispensable for the experimental neuroscientist and toxicologist, aswell as for practitioners of human and animal medicine, the book also providesan authoritative, critical, pithy reference work for specialists in publichealth and the legal profession." Oxford University Press

IllustratedYes

Dewey Decimal616.8/047

Table Of ContentPart I: Fundamentals of Experimental and Clinical Neurotoxicology1. Biological Principles of Chemical Neurotoxicity2. Human Disease3. Aspects of Veterinary NeurotoxicityPart II: Chemicals with Neurotoxic PotentialThis section presents an encyclopedic description of 450 exogenous neurotoxic chemicals/ mixtures, beginning with Absinthe and ending with Zolpidem.

Edition DescriptionRevised edition

SynopsisThis is the Bible of neurotoxicology. It is an essential reference work for any professional concerned with the neurotoxic potential of drugs, experimental agents, environmental pollutants, personal-use products, and other substances. The long-awaited Second Edition has been reorganized and completely rewritten to give encyclopedic coverage of almost 450 chemical compounds., The first edition of this highly acclaimed reference work was published in 1980. Since then no other book has approached the breadth, scholarship and the balance of this book. For this long-awaited second edition, the original editors have been joined by Albert Ludolph, who brings in expertise in biological neurotoxicology.In the introductory chapters, an overview of the biological basis of neurotoxicity provides the groundwork for discussing the scope of human and veterinary neurotoxic disease. The bulk of the text is devoted to an encyclopaedic treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic mechanisms of experimental agents and adverse effects of therapeutic and abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives and agents harboured by plants, animals and humans for use against their respective enemies are all included. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarised and cross-referenced in a series of appendices and an extensive index.This book will be indispensable to experimental neuroscientists, toxicologists, and practitioners of human and animal medicine. It also provides an authoritative, critical and pithy reference work for public health specialists and those within the legal profession., Two decades have passed since publication of the first edition of Experimental and Clinical Neurotoxicology pioneered the development of this discipline. Since then no other book has approached the breadth, scholarship, and balance of that landmark volume. For this long-awaited second edition, the original editors have been joined by Albert Ludolf, who brings expertise in biological neurotoxicology, and together with their distinguished contributors they have completely rewritten and reorganized the text. The scientific and clinical foundation is laid in three comprehensive introductory chapters. An overview of the biological basis of neurotoxicity provides the goundwork for discussing the scope of human and veterinary neurotoxic disease.The bulk of the text is devoted to an alphabetical treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions, and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic side effects of experimental agents and of therapeutic as well as abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives, and agents harbored by plants, animals, and humans for use against their respective enemies are discussed. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarized and cross-referenced in a series of appendices and an extensive index. In summary, the second edition establishes neurotoxicology as a scientific discipline that melds neurobiology, toxicology, and neurology. From this unique vantage point, the book examines in encyclopedic manner several hundred chemicals with the capacity to induce neurological illness in humans and animals. Indispensable for the experimental neuroscientist and toxicologist, as well as for practitioners of human and animal medicine, the book also provides an authoritative, critical, and pithy reference work for specialists in public health and the legal profession.

LC Classification NumberRC347.5.E96 2000