Advances in Enzymology and Related Areas of Molecular Biology Volume 76 Toone

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“Preowned condition. Copy may have the previous owner's name or personalized inscription written on ...
Level
Advanced
ISBN
9780471235842
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Product Identifiers

Publisher
Wiley & Sons, Incorporated, John
ISBN-10
0471235849
ISBN-13
9780471235842
eBay Product ID (ePID)
48056147

Product Key Features

Number of Pages
300 Pages
Language
English
Publication Name
Advances in Enzymology and Related Areas of Molecular Biology, Volume 76
Publication Year
2008
Subject
Life Sciences / Biochemistry, Chemistry / Organic
Type
Textbook
Subject Area
Science
Author
Eric J. Toone
Series
Advances in Enzymology and Related Areas of Molecular Biology Ser.
Format
Hardcover

Dimensions

Item Height
1 in
Item Weight
22 Oz
Item Length
9.1 in
Item Width
6.4 in

Additional Product Features

Intended Audience
Scholarly & Professional
Dewey Edition
21
Series Volume Number
76
Volume Number
Vol. 76
Dewey Decimal
572.6/5/4
Table Of Content
Contributors. Preface. Inosine 5'-Monophosphate Dehydrogenase (Maxim Pimkin and George D. Markham) Natural Product Glycosyltransferases: Properties and Applications (Gavin J. Williams and Jon S. Thorson). Combinatorial and Evolutionary Design of Biosynthetic Reaction Sequences (Ethan T. Johnson, Erik Holtzapple, and Claudia Schmidt-Dannert). Trends in Microbial Synthesis of Natural Products and Biofuels (Joseph A. Chemier, Zachary L. Fowler, Mattheos A. G. Koffas, and Effendi Leonard). Author Index. Subject Index.
Synopsis
Encompasses the latest advances in the field. New series editor, Daniel Purich, is a well-known biochemistand enzymologist., Advances in Enzymology and Related Areas of Molecular Biology is a seminal series in the field of biochemistry, offering researchers access to authoritative reviews of the latest discoveries in all areas of enzymology and molecular biology. These landmark volumes date back to 1941, providing an unrivaled view of the historical development of enzymology. The series offers researchers the latest understanding of enzymes, their mechanisms, reactions and evolution, roles in complex biological processes, and their applications in both the laboratory and industry. Each volume in the series features contributions from leading pioneers and investigators in the field from around the world. All articles are carefully edited to ensure thoroughness, quality, and readability. Volume 76 focuses on the most recent advances in the field of practical preparative enzymology. Enzymes have long been recognized and utilized for the preparation of specialty chemicals, and enzymatic resolution and desymmetrization are mainstays of the fine chemical industry. Today, some of the most intriguing enzymatic synthetic approaches involve the construction of complex pathways within cells to prepare molecules much more complex than those that can be reasonably developed in cell-free applications; this volume considers some of those processes. Koffas and coworkers provide an overview of the construction of complex biosynthetic pathways for the preparation of a variety of both fine and commodity chemicals, including biofuels. The development of highly efficient pathways involves a combination of rational design and, increasingly, evolutionary approaches, and Schmidt-Dannert reviews the use of evolutionary strategies in synthetic biology. Glycosylation of myriad biologically active species impacts both in vivo activity and ADME behavior. The addition of carbohydrate moieties to complex organic molecules represents a daunting synthetic challenge, and Williams and Thorson review the various strategies for enzymatic glycosylation of complex natural products. Finally, Pimkin and Markham review the structure, activity, and mechanism of inosine monophosphate dehydrogenase, a central enzyme of purine biosynthesis. With its wide range of topics and long historical pedigree, Advances in Enzymology and Related Areas of Molecular Biology can be used not only by students and researchers in molecular biology, biochemistry, and enzymology, but also by any scientist interested in the discovery of an enzyme, its properties, and its applications., This is the 76th volume in this classic series that researchers, professors, and scientists have relied on for years. It covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes.
LC Classification Number
QP552

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