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- ¡Cómpralo ya!Gastrointestinal Mucosal Defense System, Kvietys, R. 9781615041473 New<-
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N.º de artículo de eBay:127130726315
Características del artículo
- Estado
- PublishedOn
- 2014-11
- Title
- Gastrointestinal Mucosal Defense System
- ISBN
- 9781615041473
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Product Information
The gastrointestinal mucosal defense system serves to minimize mucosal injury by either ingested or endogenously produced noxious substances. The mucosal defense system is stratified into pre-epithelial (alkaline mucus), epithelial (dynamic epithelial lining), and post-epithelial (microcirculation) components. The mucus lining the epithelial surface presents a diffusional barrier to ingested material (e.g., lipids) and also serves as an unstirred layer in which a pH gradient can be established to prevent acid-induced injury. The epithelial lining prevents entrance of any toxic material to the interstitium and, should it be damaged, it is rapidly resealed by migration of adjacent viable epithelial cells to cover the defect. Any acid or other material that has entered the interstitium is washed out by an intense neurogenic hyperemia. In general, the mucosal defense system is quite effective and any adverse gastrointestinal effects associated with the normal course of nutrient assimilation are minimal. However, there are two situations in which the mucosal defense system is known to be ineffective and result in gastric mucosal injury: inadvertent ingestion of H. pylori. or intentional ingestion of NSAIDs. H. pylori can penetrate the mucus layers and cause epithelial injury and inflammation, while at the same time preventing its clearance by the host immune system. NSAIDs weaken the mucus layer and cause epithelial cell injury. Table of Contents: Acknowledgments / Introduction / The Mucus Layer / Epithelial Lining / Gastrointestinal Circulation / Integration of Mucosal Defense / Mucosal Defense System: Physiologic / Mucosal Defense System: H. pylori / Mucosal Defense System: Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) / Overall Summary and Conclusions / References / Author Biographies
Product Identifiers
Publisher
Morgan & Claypool LIFE Science Publishers
ISBN-10
1615041478
ISBN-13
9781615041473
eBay Product ID (ePID)
178389588
Product Key Features
Number of Pages
172 Pages
Language
English
Publication Name
Gastrointestinal Mucosal Defense System
Publication Year
2014
Subject
Life Sciences / Molecular Biology, Gastroenterology, Physiology
Type
Textbook
Subject Area
Science, Medical
Series
Colloquium Series on Integrated Systems Physiology: from Molecule to Function Ser.
Format
Trade Paperback
Dimensions
Item Length
9.3 in
Item Width
7.5 in
Descripción del artículo del vendedor
Información de vendedor profesional
Número de IVA: GB 724498118
CRN: 03800600
Información sobre seguridad y accesibilidad
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